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tcm herbs database


ren shen, Ginseng or Panax ginseng) or User defined compositive compound list of the TCM (compounds are denoted by PubChem_CIDs or chemical structures of … Therefore, Networks among TCM herbs, The TCMSID Version 1.0 was released. Version 1.0.1(2019-4-20). TCM-ID currently contains information for 1,588 prescriptions, 1,313 herbs, 5,669 herbal ingredients, and the 3D structure of 3,725 herbal ingredients. We have collected information on all respects of TCM including formulae, herbs and herbal ingredients.

PMC. TCM offers an extensive source of examples of this concept in which several active ingredients in one prescription are aimed at numerous targets and work together to provide therapeutic benefit. ADMET and target prediction functions were added in the tools page. Xiangya School of Pharmaceutical Sciences & (71.399%).

structural characteristics, reliability annotations, pharmacokinetic and physicochemical properties were calculated for ingredients. BACKGROUND AND PURPOSE: Traditional Chinese Medicine (TCM) is widely practised and is viewed as an attractive alternative to conventional medicine. Hoffmann ist gleichzeitig Inhaber dieses Unternehmens, das Einfuhrrechte für den Import von 100%-Naturkräuterprodukten aus Taiwan und Belgien besitzt. several key ingredients can be screened as representatives of the whole TCM to capture potential another 674 ingredients were supplemented..

permission of the authors and the original publication. The value of the data in TCM-ID was illustrated by using some of the data for an in-silico study of molecular mechanism of the therapeutic effects of herbal ingredients and for developing a computer program to validate TCM multi-herb preparations.CONCLUSIONS AND IMPLICATIONS: The development of systems biology has led to a new design principle for therapeutic intervention strategy, the concept of 'magic shrapnel' (rather than the 'magic bullet'), involving many drugs against multiple targets, administered in a single treatment. The latest version of the TCMID [ 28] database is one of the largest databases of oriental Chinese medicine, including 8,159 herbs, 43,413 ingredients, and 4,633 diseases. Chem-TCM database gathers 12070 chemical records, constituents of approximately 350 herbs used in traditional Chinese medicine. Version 1.0.10(2018-9-8).

Traditional Chinese Medicine Integrated Database (TCMID) is a comprehensive database to provide information and bridge the gap between Traditional Chinese Medicine and modern life sciences. Chen X, Zhou H, Liu YB, Wang JF, Li H, Ung CY, Han LY, Cao ZW, Chen YZ. which contains 499 herbs registered in the Chinese pharmacopoeia with 20015 ingredients including TCM-ID currently contains information for 1,588 prescriptions, 1,313 herbs, 5,669 herbal ingredients, and the 3D structure of 3,725 herbal ingredients. TCM Herbs s. r. o. wurde 2001 durch Dr. med.

It provides pictures and an overview of the source, basic nature…
JIA WEI CAN XIA TANG), Herb or Herb list (Pinyin, English or Latin name) (e.g. known drugs including FDA approved drugs with comprehensive information were added. Version 1.0.6(2019-8-7). Constructed a Traditional Chinese Medicine Simplified Integrated Database Users who use these services should cite the paper in any resulting publications. Petr Hoffmann gegründet. In this database, Europe significance degree annotations of ingredients were added. Version 1.0.7(2019-8-21).The network analysis function based on Cytoscape was added in the target page. (69.962%), 275/958 2014 Apr 16;6(1):13. TCMSP [ 29 ], a database of systems pharmacology for drug discovery contains 499 Chinese herbs, 29,384 ingredients, and 3,311 targets. The Traditional Chinese Medicine Information Database TCM-ID, at http://tcm.cz3.nus.edu.sg/group/tcm-id/tcmid.asp, was introduced for providing comprehensive information about all aspects of TCM including prescriptions, constituent herbs, herbal ingredients, molecular structure and functional properties of active ingredients, therapeutic and side effects, clinical indication and application and related matters.RESULTS: TCM-ID currently contains information for 1,588 prescriptions, 1,313 herbs, 5,669 herbal ingredients, and the 3D structure of 3,725 herbal ingredients.

Provided specific structure category of each ingredient; Evaluated 8 commonly used physicochemical properties; Provided potential targets of ingredients by multi target prediction tools; Constructed the networks between herbs and potential targets; Version 1.1.0(2020-5-5). Use services and download of the data, in whole or in part, for commercial purposes requires explicit TCMSID, a Traditional Chinese Medicine Simplified Integrated Database, potential targets of ingredients based on muti-tool were predicted. There are over 9,500 unique molecular records adjusted for overlapping presence in multiple plants and different stereochemistry. Central South University. targets via implementing multi-tool target prediction. TCM-ID was introduced for providing comprehensive information about all aspects of TCM including prescriptions, constituent herbs, herbal ingredients, molecular structure and functional properties of active ingredients, therapeutic and side effects, clinical indication and application and related matters. Version 1.0.9(2019-9-5). Version 1.0.2(2019-5-23). 449 herbs with 17246 ingredients with comprehensive information were added.. databases.

The database consists of four major parts: chemical identification, botanical information, predicted activity against common Western therapeutic targets, and estimated molecular activity according to traditional Chinese herbal medicine categories. formulations, ingredients, potential targets can be constructed to facilitate clarifying function and mechanisms of the TCM. a catalog of biological The database and its mining applications described here represent early efforts toward exploring TCM for new theories in drug discovery. Version 1.0(2019-3-1). comprehensive annotations, was developed to achieve TCM Simplification. Added the whole standard formulation simplify pipeline. TCMSID, a Traditional Chinese Medicine Simplified Integrated Database, which contains 499 herbs registered in the Chinese pharmacopoeia with 20015 ingredients including comprehensive annotations, was developed to achieve TCM Simplification.

Version 1.0.8(2019-9-01). Wie bereits … Version 1.0.4(2019-6-30). 1411/4694 College of Life Sciences, Zhejiang University, Hangzhou, Zhejiang, China. Version 1.0.3(2019-6-9). We have also collected information for drugs, diseases which are deeply studied by modern pharmacology … Version 1.0.5(2019-7-22). Dr. med. chemical similarity search function was added in the tools page.

Chem-TCM is the digital database of individual molecules, constituents of plants used in the traditional Chinese herbal medicine. Three alternative input types: TCM formula (Pinyin name) (e.g. TCMSP: a database of systems pharmacology for drug discovery from herbal medicines. containing 20015 herbal ingredients; Evaluated key herbal ingredients that exert pharmacological effects; Evaluated the main active ingredients in traditional Chinese medicine; Evaluated 14 kinds of ADME/T properties for all ingredients; Evaluated the structural reliability of all ingredients. Quantitative information about TCM prescriptions, constituent herbs and herbal ingredients is necessary for studying and exploring TCM.EXPERIMENTAL APPROACH: We manually collected information on TCM in books and other printed sources in Medline. TCM-ID was introduced for providing comprehensive information about all aspects of TCM including prescriptions, constituent herbs, herbal ingredients, molecular structure and functional properties of active ingredients, therapeutic and side effects, clinical indication and application and related matters.
License Agreement: TCMSP is made available under the Open Database License: http://opendatacommons.org/licenses/odbl/1.0/ . This database contains information on the most commonly used Traditional Chinese Medicine (TCM) herbs.

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